Thermo Fisher Scientific KLF3 Polyclonal Antibody
KLF3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, ELISA에 적합합니다. Human 시료에 반응하며, Affinity Chromatography로 정제된 액상 제품입니다. PBS/glycerol buffer에 보관하며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–240 of human KLF3 (NP_057615.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855294 |
Product Specific Information
Immunogen sequence:
MLMFDPVPVK QEAMDPVSVS YPSNYMESMK PNKYGVIYST PLPEKFFQTP EGLSHGIQME PVDLTVNKRS SPPSAGNSPS SLKFPSSHRR ASPGLSMPSS SPPIKKYSPP SPGVQPFGVP LSMPPVMAAA LSRHGIRSPG ILPVIQPVVV QPVPFMYTSH LQQPLMVSLS EEMENSSSSM QVPVIESYEK PISQKKIKIE PGIEPQRTDY YPEEMSPPLM NSVSPPQALL QENHPSVIVQ
Target Information
Krueppel-like factors (KLFs) are a family of evolutionarily conserved zinc finger-containing transcription factors involved in cell growth, proliferation, differentiation, and embryogenesis. Members of the Sp1-like/KLF family may function as activators or repressors depending on promoter binding and coregulator interactions.
KLF6 (Zf9/CPBP) and KLF3 are Kruppel-like zinc finger transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates collagen I promoter-driven genes, suggesting a role in tissue injury response. KLF3 may play a role in hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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