Thermo Fisher Scientific VSIG2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Immunogen sequence:
GKKPKETYGG SDLREDAIAP GISEHTCMRA DSSKGFLERP SSASTVTTTK SKLPMVV

Antigen sequence identity:

• Mouse: 70%
• Rat: 74%

Target Information

CTXL, a cortical thymocyte marker, is a member of the immunoglobulin (Ig) superfamily and has features of both antigen-specific receptors and adhesion molecules.
This single-pass, type I protein includes a signal peptide, an extracellular V-type Ig-like domain followed by a C2-type Ig-like domain, and a cytoplasmic tail.
Expression levels are high in stomach, colon, prostate, trachea, and thyroid gland, with lower levels in bladder and lung tissues.
CTXL is not expressed in the thymus and is developmentally regulated, possibly involved in thymocyte selection.
It localizes to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion and leukocyte transmigration.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.