Thermo Fisher Scientific SPIRE1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SPIRE1. Recombinant protein control fragment (Product #RP-98282). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPIRE1,uniProtId:Q08AE8-1,ncbiNodeId:9606,antigenRange:646-734,antigenLength:756,antigenImageFileName:PA5-59362_SPIRE1_Q08AE8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59362_SPIRE1_Q08AE8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647869

Product Specific Information

Immunogen sequence: LQRGESSMRS EKPSTAHHRP LRSIARFSSK SKSMDKSDEE LQFPKELMED WSTMEVCVDC KKFISEIISS SRRSLVLANK RARLKRKTQ

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.