Thermo Fisher Scientific HABP4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HABP4. Recombinant protein control fragment (Product #RP-101784). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HABP4,uniProtId:Q5JVS0-1,ncbiNodeId:9606,antigenRange:197-279,antigenLength:413,antigenImageFileName:PA5-63225_HABP4_Q5JVS0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63225_HABP4_Q5JVS0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642296

Product Specific Information

Immunogen sequence: RGGPGNRVFD AFDQRGKREF ERYGGNDKIA VRTEDNMGGC GVRTWGSGKD TSDVEPTAPM EEPTVVEESQ GTPEEESPAK VPE

Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 75%.

Target Information

RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594). Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation (PubMed:19523114). Binds (via C-terminus) to poly(U) RNA (PubMed:19523114). Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594). Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.