Thermo Fisher Scientific SPAG4 Polyclonal Antibody
인간 SPAG4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 생식세포 구조 연구에 적합한 연구용 항체.
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Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPAG4. Recombinant protein control fragment (Product #RP-100903) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647777 |
Product Specific Information
Immunogen sequence:
PLENEPKEML TLSEYHERVR SQGQQLQQLQ AELDKLHKEV STVRAANSER VAKLVFQRLN EDFVRKPDYA LSSVGASIDL QKTSHDYAD- Highest antigen sequence identity to orthologs:
- Mouse: 89%
- Rat: 89%
Target Information
The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme:
- Outer dense fibers surrounding the axoneme in the midpiece and principal piece
- Fibrous sheath surrounding the outer dense fibers in the principal piece of the tail
Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility.
In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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