Thermo Fisher Scientific Human TAOK2 (TAO1), GST Tag Recombinant Protein

Thermo Fisher Scientific Human TAOK2 (TAO1), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
• For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
• Do not store kinase diluted.
• Properly stored at -80°C, guaranteed for 6 months from date of purchase.
• Protein Form: Catalytic

Target Information

TAOK2 (TAO1) is a serine/threonine kinase that may regulate the stress-responsive p38 MAP kinase pathway. In vitro, TAO2 activates MAP/ERK kinases (MEK) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). Research suggests TAO kinases play an essential role in signaling from physiological agonists to the p38 MAPK pathway (Chen et al., 2003). Autophosphorylation of TAO may be involved in its activation mechanism, with Ser181 located within the MEK binding domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.