Thermo Fisher Scientific PHF6 Polyclonal Antibody
PHF6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 4°C에서 보관하며, FFPE 조직의 IHC 시 citrate buffer(pH 6.0) 전처리 권장. 인간 PHF6 항원(315-365 aa)에 대해 제작되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 315 and 365 of human PHD finger protein 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Predicted reactivity (based on 100% sequence identity): Mouse, Bovine, Orangutan
Target Information
This gene belongs to the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, suggesting a role in transcriptional regulation and nucleolar localization.
Mutations in this gene are associated with Borjeson-Forssman-Lehmann syndrome (BFLS), characterized by intellectual disability, epilepsy, hypogonadism, hypometabolism, obesity, facial swelling, narrow palpebral fissures, and large ears.
Alternative splice variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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