Thermo Fisher Scientific Stabilin 2 Polyclonal Antibody
Thermo Fisher Scientific의 Stabilin 2 폴리클로날 항체로 인간 Stabilin-2 단백질을 검출. Western blot에 적합하며 E. coli 유래 항원 사용. 낮은 교차반응성, 동결건조 형태, -20°C 보관.
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- PA547522
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Thermo Fisher Scientific Stabilin 2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.1 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Stabilin-2 (Gly2198–Val2295) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606336 |
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human Stabilin-1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging.
The protein contains:
- 7 fasciclin domains
- 15 epidermal growth factor (EGF)-like domains
- 2 laminin-type EGF-like domains
- C-type lectin-like hyaluronan-binding Link module
The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node.
It binds and endocytoses ligands such as:
- Hyaluronan
- Low density lipoprotein
- Gram-positive and Gram-negative bacteria
- Advanced glycosylation end products
Supporting its possible role as a scavenger receptor, the protein cycles between the plasma membrane and lysosomes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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