Thermo Fisher Scientific TMEM43 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Published species

Fruit fly

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 80-310 of human TMEM43 (NP_077310.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM43,uniProtId:Q9BTV4-1,ncbiNodeId:9606,antigenRange:80-310,antigenLength:400,antigenImageFileName:PA5-110497_TMEM43_Q9BTV4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110497_TMEM43_Q9BTV4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855908

Product Specific Information

Immunogen sequence: VAPENEGRLV HIIGALRTSK LLSDPNYGVH LPAVKLRRHV EMYQWVETEE SREYTEDGQV KKETRYSYNT EWRSEIINSK NFDREIGHKN PSAMAVESFM ATAPFVQIGR FFLSSGLIDK VDNFKSLSLS KLEDPHVDII RRGDFFYHSE NPKYPEVGDL RVSFSYAGLS GDDPDLGPAH VVTVIARQRG DQLVPFSTKS GDTLLLLHHG DFSAEEVFHR ELRSNSMKTW G

Target Information

This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.