Thermo Fisher Scientific PPAT Monoclonal Antibody (OTI1B11), TrueMAB
PPAT 단백질을 인식하는 Mouse monoclonal 항체로 Western blot과 IHC(Paraffin)에 적합. Human 시료 반응성. Lyophilized 형태로 제공되며, PBS(pH 7.3, 8% trehalose) 버퍼에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 42–278 of human PPAT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PPAT protein is a member of the purine/pyrimidine phosphoribosyltransferase family.
It functions as a regulatory allosteric enzyme catalyzing the first step of de novo purine nucleotide biosynthesis.
The PPAT gene and the PAICS/AIRC gene, encoding a bifunctional enzyme catalyzing steps six and seven in the same pathway, are located in close proximity on chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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