Thermo Fisher Scientific GCP5 Polyclonal Antibody
Human GCP5 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 완충액에 보존. 감마튜불린 복합체 연구용에 적합.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GCP5. Recombinant protein control fragment (Product # RP-98101) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641925 |
Product Specific Information
Immunogen sequence:
DWGKYLMEDE EMDIGPYMDT PNWSEESEEE NDQQPLSRED SGIQVDRTPL EEQDQNRKLD PCISWKDEPD DRSWLEHHVV HQYWTARPSQ FPHSLHLHSN LAAVW
Highest antigen sequence identity to orthologs:
- Mouse: 75%
- Rat: 76%
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the associated proteins GCP2, GCP3, GCP4, GCP5, and GCP6, all essential components of microtubule organizing centers. These components localize to both the centrosome, where they assist in microtubule nucleation, and the cytoplasm, where they exist as soluble complexes that can be recruited as needed.
GCP5 (gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1,024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Mutations in the GCP5 gene are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior, and lower intellectual ability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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