Thermo Fisher Scientific ISCU Polyclonal Antibody
Human ISCU 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 단기 4°C, 장기 -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ISCU. Recombinant protein control fragment (Product # RP-102840) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642788 |
Product Specific Information
Immunogen sequence:
TFGCGSAIAS SSLATEWVKG KTVEEALTIK NTDIAKELCL PPVKLHCSML AEDAIKAALA DYKLKQEPK
Sequence identity:
- Mouse: 99%
- Rat: 99%
Target Information
Iron-sulfur (Fe-S) clusters are essential for several mitochondrial enzymes and other subcellular compartment proteins. They consist of sulfur and iron, and are synthesized through multiple steps involving cysteine desulfurases, iron donors, chaperones, and scaffold proteins.
The ISCU gene encodes two isomeric forms, ISCU1 and ISCU2, which serve as Fe-S cluster scaffold proteins. Mutations in this gene are associated with myopathy characterized by severe exercise intolerance and myoglobinuria.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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