Thermo Fisher Scientific GCKR Polyclonal Antibody
Thermo Fisher Scientific의 GCKR Polyclonal Antibody는 인간 GCKR 단백질을 인식하는 토끼 폴리클로날 항체입니다. ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS와 글리세롤 버퍼에 보관되며 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GCKR. Recombinant protein control fragment (Product #RP-107327) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663292 |
Product Specific Information
Immunogen sequence:
EDWSSTFRQVA ERMQKMQEKQ KAFVLNPAIG PEGLSGSSRM KGGSATKILL ETLLLAAHKT VDQGIAASQR CLLEILRTFE RAHQVTYSQS PKIATLMKSV STSL
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 90%
Target Information
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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