Thermo Fisher Scientific Bcl-6 (Follicular Lymphoma Marker) Recombinant Rabbit Monoclonal Antibody (BCL6/8808R)
Bcl-6 단백질을 표적하는 재조합 토끼 단클론 항체로, 인간 시료에 반응하며 IHC(P)에서 1–2 µg/mL로 사용 가능. B세포 림프종 및 호지킨 림프종 연구에 적합. Protein A/G로 정제된 액상 항체로 4°C 보관.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BCL6/8808R |
| Immunogen | Recombinant fragment (aa1–400) of human BCL6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Raji or Ramos cells, human tonsil, or Hodgkin’s lymphoma
- Cellular Location: Nucleus
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and rearrangements have been detected in 33–45% of diffuse large B-cell lymphomas.
It has been detected immunohistochemically in follicular lymphomas, diffuse large B-cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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