Thermo Fisher Scientific NLGN4X Monoclonal Antibody (5A11)
NLGN4X 단백질을 인식하는 Mouse monoclonal 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, 신경 시냅스 관련 단백질 연구 및 자폐 스펙트럼 장애 관련 연구에 활용 가능합니다. 액상 형태로 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A11 |
| Immunogen | NLGN4X (NP_065793, a.a. 577–676) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RVRDHYRATK VAFWLELVPH LHNLNEIFQY VSTTTKVPPP DMTSFPYGTR RSPAKIWPTT KRPAITPANN PKHSKDPHKT GPEDTTVLIE TKRDYSTELS
Target Information
Neuroligin-4, X-linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge the synaptic cleft and play an essential role in synaptic transmission between neurons. There are five neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X have been linked to Autism Spectrum Disorders (ASD). Expression of NLGN4X has been reported in human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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