
Thermo Fisher Scientific OPRD1 Polyclonal Antibody
OPRD1 단백질을 인식하는 토끼 폴리클로날 항체로 Western blot 및 면역세포화학에 적합. 인간 및 생쥐 시료 반응성. 친화 크로마토그래피로 정제된 액상 항체로, PBS 및 글리세롤 완충액에 보존. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OPRD1 (Accession P41143), corresponding to amino acid residues C337–A372 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851573 |
Product Specific Information
This antibody detects endogenous levels of total OPRD1.
Target Information
OPRD1 (Opioid Receptor Delta 1) is involved in the regulation of anxiety, depression, and pain. It is considered a promising therapeutic target for mood disorders and drug addiction. Delta and kappa opioid receptors can form heterodimers, functioning synergistically. OPRD1 expression is primarily found in the brain, with high levels in the cortex, caudate, hippocampus, nucleus accumbens, and putamen, and lower levels in the cerebellum, hypothalamus, substantia nigra, and thalamus. Reduced OPRD1 expression has been observed in the putamen and amygdala of Alzheimer’s patients and in the putamen in Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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