Thermo Fisher Scientific PDCD6 Monoclonal Antibody (2B4)
PDCD6 단백질을 인식하는 Mouse IgG2a 형 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
- 카탈로그번호
- H00010016-M01A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B4 |
| Immunogen | PDCD6 (AAH12384.1, 92 a.a. approximately 191 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ITDWQNVFRT YDRDNSGMID KNELKQALSG FGYRLSDQFH DILIRKFDRQ GRGQIAFDDF IQGCIVLQRL TDIFRRYDTD QDGWIQVSYE QYLSMVFSIV
Target Information
An increased intracellular Ca²⁺ concentration induces apoptotic cell death. Transiently elevated Ca²⁺ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis.
ALG-2 (apoptosis-linked gene 2) is a Ca²⁺-binding protein that participates in regulatory events occurring late in the apoptotic program, where several death signals converge. ALG-2 is expressed in normal brain and more abundantly in ischemic brain.
The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, including Calpain small subunits sorcin and Grancalcin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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