Thermo Fisher Scientific CD13/Aminopeptidase-N (Myeloid Cell Marker) Monoclonal Antibody (APN/6997)
CD13/Aminopeptidase-N 단백질을 인식하는 Mouse 단클론 항체로, Western blot, IHC, ELISA 등 다양한 응용에 적합. Human 시료에 반응하며, Protein A/G로 정제된 액상 형태. 세포 표지 및 면역학 연구용으로 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | APN/6997 |
| Immunogen | Recombinant fragment (around aa50–250) of human ANPEP protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4 °C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It catalyzes the removal of neutral amino acids from small peptides, regulating activation or inactivation of bioactive peptides. CD13 is involved in extracellular matrix degradation, antigen processing, and signal transduction, and plays roles in inflammation, intercellular contact, cell motility, and vascularization.
It is expressed by granulocytes, monocytes, and myeloid leukemia cells, and its expression is associated with poor prognosis in carcinomas. CD13 also functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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