Thermo Fisher Scientific HTR1B Polyclonal Antibody
HTR1B 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, 인간 및 마우스에 반응합니다. Western blot에 최적화되어 있으며, TBS 버퍼에 0.5 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA518520
- 판매단위
- pk
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SNEDFKQAFHK) corresponding to the C-terminus amino acids of HTR1B (aa 372–382) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977551 |
Product Specific Information
- Predicted to react with bovine, canine, feline, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Serotonin (5-hydroxytryptamine, 5-HT) is a serum factor involved in regulating diverse biological processes in the central and peripheral nervous systems, cardiovascular system, and gastrointestinal system.
Molecular cloning studies have identified five receptors belonging to the 5-HT1 subtypes, which are negatively coupled to adenylyl cyclase.
Radioligand binding studies indicate the presence of 5-HT1B (formerly 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior colliculus.
In situ hybridization studies reveal abundant 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus, and lower levels in caudate-putamen, cortical areas, thalamic, and hypothalamic nuclei.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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