
ELK Biotechnology KPCD3 rabbit pAb
인간 및 생쥐 단백질을 인식하는 KPCD3 rabbit polyclonal antibody. WB와 ELISA에 적합하며, 세포질 및 세포막에서 발현되는 단백질 검출에 활용 가능. 안정적인 IgG 아이소타입으로 -20°C에서 1년 보관 가능.
- 판매단위
- pk
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제품명
KPCD3 rabbit pAb
제품 개요
KPCD3 rabbit polyclonal antibody는 인간 단백질의 특정 영역에서 합성된 펩타이드를 면역원으로 제작된 항체입니다. 세린/트레오닌 키나아제 계열의 단백질을 인식하며, WB 및 ELISA 실험에서 높은 특이성과 재현성을 제공합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 97 kD |
| Gene ID (Human) | 23683 |
| Human Swiss-Prot No. | O94806 |
| Cellular Localization | Cytoplasm, Membrane. Translocation to the cell membrane is required for kinase activation. |
| Species Reactivity | Human; Mouse |
Background
This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. (RefSeq, Jan 2015)
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