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ELK Biotechnology JAML1 rabbit pAb
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ELK Biotechnology JAML1 rabbit pAb

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JAML1 단백질에 특이적인 토끼 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 세포막 단백질 검출에 유용하며, 인간, 랫드, 마우스 시료에서 반응합니다. 고순도의 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.

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pk
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ELK Biotechnology ES10721-100UL JAML1 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES10721-50UL JAML1 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology JAML1 rabbit pAb

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JAML1 rabbit pAb

제품 정보

항목 내용
Applications WB; ELISA
Recommended Dilutions WB 1:500–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from part region of human protein
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 43 kD
Gene ID (Human) 120425
Human Swiss-Prot No Q86YT9
Cellular Localization Cell membrane; Single-pass type I membrane protein; Cell junction; Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515)
Species Reactivity Human; Rat; Mouse

Background

  • Domain: The Ig-like V-type domain 2 mediates interaction with CXADR.
  • Function: May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.
  • Induction: Up-regulated upon retinoic acid, Me2SO, and PMA treatment in differentiating myeloid leukemia cells.
  • Similarity: Belongs to the immunoglobulin superfamily; contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Subcellular Location: Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.
  • Subunit: Interacts with CXADR.
  • Tissue Specificity: Expression is restricted to hematopoietic tissues except liver. Expressed in fetal liver, spleen, and thymus.

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