ELK Biotechnology M3K12 rabbit pAb
ELK Biotechnology의 M3K12 rabbit pAb는 인간, 생쥐, 랫트 시료에 반응하는 다클론 항체입니다. WB와 ELISA에 사용 가능하며, 세포질 및 세포막 단백질 검출에 적합합니다. 신경세포에서 발현되는 단백질 인산화 조절 연구에 유용합니다.
- 판매단위
- pk
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제품명
M3K12 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 730–810) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 94 kD |
| Gene ID (Human) | 7786 |
| Human Swiss-Prot No. | Q12852 |
| Cellular Localization | Cytoplasm, Cell membrane. Behaves essentially as an integral membrane protein. |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals is regulated by membrane depolarization via calcineurin. It forms heterodimers with leucine zipper-containing transcription factors such as CREB and MYC, playing a regulatory role in PKA or retinoic acid-induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.
[provided by RefSeq, Jul 2010]
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