ELK Biotechnology VATC1 rabbit pAb
VATC1 rabbit pAb는 인간, 랫트, 마우스에서 반응하는 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 세포 내 소포막 단백질을 인식하며, V-ATPase 복합체 연구에 활용됩니다. 고순도 IgG 항체로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
VATC1 rabbit pAb
적용 분야
- WB (Western Blot)
- ELISA
권장 희석 배율
- WB: 1:500–1:2000
- ELISA: 1:5000–1:20000
제품 스펙
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from part region of human protein |
| Species Reactivity | Human, Rat, Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 42 kD |
| GeneID (Human) | 528 |
| Human Swiss-Prot No | P21283 |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. |
| Storage | -20°C / 1 year |
| Host | Rabbit |
제품 설명 (Background)
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c’, c’’, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins.
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