ELK Biotechnology UTRO rabbit pAb

ELK Biotechnology UTRO rabbit pAb

제품 설명

UTRO rabbit pAb는 인간 단백질의 특정 부분에서 합성된 펩타이드를 면역원으로 제작된 토끼 폴리클로날 항체입니다. 본 항체는 세포 접합부, 시냅스, 세포골격 등에서 발현되는 UTRO 단백질을 검출하는 데 사용됩니다.

제품 정보

Background

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. (provided by RefSeq, Jul 2008)