ELK Biotechnology UB2E3 rabbit pAb
UB2E3 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 인간, 마우스 시료에 반응하며, 핵과 세포질에 위치한 단백질 검출에 사용됩니다. 고농도(1 mg/ml)로 -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology UB2E3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | UB2E3 rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 22 kD |
| GeneID (Human) | 10477 |
| Human Swiss-Prot No | Q969T4 |
| Cellular Localization | Nucleus, Cytoplasm. Shuttles between the nucleus and cytoplasm in an IPO11-dependent manner. |
| Species Reactivity | Human; Mouse |
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, indicating that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
[provided by RefSeq, Jun 2013]
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