
ELK Biotechnology TPSN rabbit pAb
TPSN rabbit pAb는 인간 및 마우스 시료에 반응하는 다클론 항체로, WB 및 ELISA에 적합합니다. 인간 단백질 유래 합성 펩타이드로 면역화되었으며, 49kD 밴드를 검출합니다. -20°C에서 1년간 보관 가능하며, ER 막 단일 통과형 단백질 인식에 활용됩니다.
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제품명
TPSN rabbit pAb
적용 분야
- WB
- ELISA
권장 희석 배율
- WB: 1:500–1:2000
- ELISA: 1:5000–1:20000
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from part region of human protein |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 49 kD |
| GeneID (Human) | 6892 |
| Human Swiss-Prot No | O15533 |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
| Storage | -20°C / 1 year |
| Host | Rabbit |
배경
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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