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Thermo Fisher Scientific TRPV6 Polyclonal Antibody, FITC

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TRPV6 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, IP 등 다양한 면역분석에 사용됩니다. 사람, 마우스, 랫트 시료에 반응하며, 형광 검출(Ex/Em 498/517 nm)에 적합합니다. 연구용으로만 사용 가능합니다.

카탈로그번호: TRPV6-FITC
브랜드: Thermo Fisher Scientific
카테고리: Polyclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 05. 오전 12:12

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Thermo Fisher Scientific TRPV6-FITC TRPV6 Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·

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594,400원VAT 포함 653,840원

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Thermo Fisher Scientific · Thermo Fisher Scientific TRPV6 Polyclonal Antibody, FITC

Applications and Tested Dilutions

Application	Tested Dilution
Western Blot (WB)	1:500–1:1,000
ELISA	1:10,000
Immunoprecipitation (IP)	1:50–1:250

Product Specifications

항목	내용
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide from amino acids 700–732 of TRPV6 protein. The peptide was covalently modified and coupled to a carrier protein using a heterobifunctional cross linker.
Conjugate	FITC
Excitation / Emission Max	498 / 517 nm
Form	Liquid
Concentration	0.5–1.5 mg/mL
Purification	Affinity chromatography
Storage Buffer	Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA
Contains	0.02% sodium azide
Storage Conditions	-20°C, store in dark
Shipping Conditions	Ambient (domestic); Wet ice (international)

Target Information

Calcium-permeable channels such as TRPV6 play roles in neurotransmission, muscle contraction, and exocytosis by providing calcium as an intracellular second messenger. Depending on tissue type, transcellular calcium transport may be regulated by vitamin D, parathyroid hormone (PTH), or calcitonin (CALCA).
TRPV6 is a calcium-selective cation channel involved in Ca²⁺ uptake and reabsorption in various tissues, including the intestine. The channel is activated by low internal calcium levels and exhibits inward rectification. Inactivation occurs via both rapid Ca²⁺-dependent and slower Ca²⁺-calmodulin-dependent mechanisms, possibly regulated by phosphorylation.
It is slowly inhibited by Mg²⁺ in a voltage-independent manner in vitro. Heteromeric assembly with TRPV5 modifies channel properties, and TRPV5–TRPV6 heteromultimers show voltage-dependent gating. TRPV6 interacts with TRPV5, S100A10, ANAX2–S100A10 heterotetramer, BSPRY, and calmodulin. The interaction with S100A10 is required for trafficking to the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.