Thermo Fisher Scientific TRPV6 Polyclonal Antibody, FITC
TRPV6 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, IP 등 다양한 면역분석에 사용됩니다. 사람, 마우스, 랫트 시료에 반응하며, 형광 검출(Ex/Em 498/517 nm)에 적합합니다. 연구용으로만 사용 가능합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from amino acids 700–732 of TRPV6 protein. The peptide was covalently modified and coupled to a carrier protein using a heterobifunctional cross linker. |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calcium-permeable channels such as TRPV6 play roles in neurotransmission, muscle contraction, and exocytosis by providing calcium as an intracellular second messenger. Depending on tissue type, transcellular calcium transport may be regulated by vitamin D, parathyroid hormone (PTH), or calcitonin (CALCA).
TRPV6 is a calcium-selective cation channel involved in Ca²⁺ uptake and reabsorption in various tissues, including the intestine. The channel is activated by low internal calcium levels and exhibits inward rectification. Inactivation occurs via both rapid Ca²⁺-dependent and slower Ca²⁺-calmodulin-dependent mechanisms, possibly regulated by phosphorylation.
It is slowly inhibited by Mg²⁺ in a voltage-independent manner in vitro. Heteromeric assembly with TRPV5 modifies channel properties, and TRPV5–TRPV6 heteromultimers show voltage-dependent gating. TRPV6 interacts with TRPV5, S100A10, ANAX2–S100A10 heterotetramer, BSPRY, and calmodulin. The interaction with S100A10 is required for trafficking to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Precision Circulating Water Bath, Precision CIR 19
5,341,100원
Thermo Fisher Scientific
Thermo Fisher Scientific Precision Coliform Water Baths, Precision COL 19
6,561,000원
Thermo Fisher Scientific
Thermo Fisher Scientific TRPV6 Polyclonal Antibody, FITC
594,400원
Thermo Fisher Scientific
Thermo Fisher Scientific CryoMed Controlled-Rate Freezer, General Purpose
42,390,300원
Thermo Fisher Scientific
Thermo Fisher Scientific C15orf42 Polyclonal Antibody, Biotin
594,400원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|