Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI4G2), TrueMAB
PTPRE 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. HEK293T 세포에서 발현된 인간 재조합 단백질을 면역원으로 사용하였으며, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G2 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which are signaling molecules regulating various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants have been reported:
- One encodes a receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- The other encodes a nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies in mice suggest regulatory roles of this PTP in RAS-related signal transduction pathways, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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