Thermo Fisher Scientific Calmodulin 3 Polyclonal Antibody
Calmodulin 3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Pig, Rat 간 높은 상동성(100%)을 보입니다. 합성 펩타이드(aa 49-98) 기반 면역원으로 제작되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human Calmodulin (aa 49–98) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691194 |
Product Specific Information
This target displays homology in the following species:
- Human: 100%
- Pig: 100%
- Rat: 100%
Target Information
Calcium binding proteins (CaBP) play a crucial role in calcium-mediated cellular signal transduction in the central nervous system. The CaBP family shares similarity with CaM I (calmodulin), and CaBP proteins can functionally substitute for or augment CaM I.
CaBP7 (Calcium-binding protein 7) contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
CaBP7 and 8 possess a unique targeting mechanism among CaBPs, contributing to differential Ca²⁺-sensing by these family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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