Thermo Fisher Scientific CD28 Monoclonal Antibody (CB28), PE
인간 CD28 항원을 인식하는 Mouse IgG1 단클론 항체로 PE 형광표지. Flow cytometry 및 Immunocytochemistry에 적합. Protein A/G 정제, 4°C 암소 보관. 연구용으로만 사용.
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Thermo Fisher Scientific CD28 Monoclonal Antibody (CB28), PE
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 5 µL / 10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CB28 |
| Immunogen | Recombinant human CD28 protein |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Wet ice |
Additional Formats
- Unconjugated
- CF 488
- Request custom conjugation available
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T-cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily, constitutively expressed on most peripheral blood T lymphocytes. CD28 serves as a critical costimulatory receptor, providing the second activation signal by binding CD80 and CD86 on antigen-presenting cells. It prevents T cells from entering an anergic state or premature apoptosis. In murine models, CD28 is expressed on all CD4⁺ and CD8⁺ T cells in peripheral lymphoid organs and blood. Expression varies during thymocyte maturation stages. Dysregulation of CD28 is associated with diseases such as mycosis fungoides and Sezary’s disease.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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