ELK Biotechnology ADA11 rabbit pAb
인간 ADA11 단백질을 인식하는 토끼 다클론 항체로 WB 실험에 적합합니다. 막 단백질 검출에 유용하며, 85kD 밴드 확인 가능. 고순도 IgG 형식으로 -20°C에서 1년 보관 가능.
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제품명
ADA11 rabbit pAb
제품 개요
ELK Biotechnology의 ADA11 rabbit pAb는 인간 ADA11 단백질을 인식하는 토끼 유래 다클론 항체입니다. ADAM 단백질 패밀리에 속하는 막 결합형 단백질 검출에 적합하며, WB 실험에서 안정적인 결과를 제공합니다.
제품 상세 정보
| 항목 | 내용 |
|---|---|
| Product name | ADA11 rabbit pAb |
| Alternative Names | Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11), Metalloproteinase-like, disintegrin-like, and cysteine-rich protein (MDC) |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human ADA11 (AA range: 600–650) |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 85 kD |
| GeneID (Human) | 4185 |
| Human Swiss-Prot No | O75078 |
| Cellular localization | Membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse |
배경 정보
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.
The encoded preproprotein is proteolytically processed to generate the mature protease.
This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.
Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
[provided by RefSeq, Jan 2016]
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