ELK Biotechnology ATL2 rabbit pAb
ADAMTSL-2 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. WB 실험에 적합하며, 권장 희석비는 1:500–2000입니다. ATL2 단백질의 194–244 아미노산 서열에서 유래한 펩타이드로 면역화되었습니다. -20°C에서 1년 보관 가능합니다.
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- ES18200-xxxxx (2개 옵션)
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제품명
ATL2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ADAMTS-like protein 2 (ADAMTSL-2) |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human ATL2 (AA range: 194–244) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 105 kD |
| Gene ID (Human) | 9719 |
| Human Swiss-Prot No. | Q86TH1 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Mouse |
Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The protein encoded by this gene lacks the protease domain and is therefore a member of the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds to the cell surface and extracellular matrix, and interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
[Provided by RefSeq, Feb 2009]
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