ELK Biotechnology Axl (phospho-Tyr702) rabbit pAb
Axl 인산화 타이로신(Tyr702)을 인식하는 토끼 폴리클로날 항체로, WB에 적합하며 1:1000–2000 희석 권장. 인간, 쥐, 생쥐 반응성. 세포막 단일 통과형 단백질 검출에 사용. -20°C 보관 시 1년 안정.
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제품명
Axl (phospho-Tyr702) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human Axl (Tyr702) |
| Host Species | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 130 kD |
| Gene ID (Human) | 558 |
| Human Swiss-Prot No. | P30530 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
[provided by RefSeq, Jul 2008]
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