Thermo Fisher Scientific Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) Monoclonal Antibody (SPM191)
인체 KRT20 단백질을 인식하는 단클론 항체로, 결장 상피세포 마커로 사용됩니다. Western blot 및 면역조직화학(IHC)에 적합하며, Protein A/G로 정제된 액상 형태입니다. 보존제 없이 PBS(pH 7.4)에 보관하며, -20°C에서 냉동 보관합니다.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM191 |
| Immunogen | Recombinant fragment of human KRT20 protein (around aa 196–323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12–q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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