Thermo Fisher Scientific ACTL7B Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ACTL7B (NP_006677.1, 1 a.a. approximately 415 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Actin-like 7B,uniProtId:Q9Y614-1,ncbiNodeId:9606,antigenRange:1-415,antigenLength:415,antigenImageFileName:H00010880-D01P_Actin-like_7B_Q9Y614-1_Rabbit.svg,antigenImageFileNamePDP:H00010880-D01P_Actin-like_7B_Q9Y614-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MATRNSPMPL GTAQGDPGEA GTRPGPDASL RDTGAATQLK MKPRKVHKIK AVIIDLGSQY CKCGYAGEPR PTYFISSTVG KRCPEAADAG DTRKWTLVGH ELLNTEAPLK LVNPLKHGIV VDWDCVQDIW EYIFRTAMKI LPEEHAVLVS DPPLSPSSNR EKYAELMFET FGIPAMHVTS QSLLSIYSYG KTSGLVVESG HGVSHVVPIS EGDVLPGLTS RADYAGGDLT NYLMQLLNEA GHAFTDDHLH IIEHIKKKCC YAAFLPEEEL GLVPEELRVD YELPDGKLIT IGQERFRCSE MLFQPSLAGS TQPGLPELTA ACLGRCQDTG FKEEMAANVL LCGGCTMLDG FPERFQRELS LLCPGDSPAV AAAPERKTSV WTGGSILASL QAFQQLWVSK EEFEERGSVA IYSKC

Target Information

The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene, and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.