Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI1G5), TrueMAB
Human TGIF1 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화되어 있음. TrueMAB 포맷으로 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol buffer 내 액상 형태로 제공되며 -20°C에서 안정 저장 가능.
- 카탈로그번호
- TA802282
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G5 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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