Thermo Fisher Scientific Endonuclease IV, E.coli (2 U/μL)
| 상품 옵션 정보 | ||||||||
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| 카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
| EN0591 | - | Thermo Fisher Scientific EN0591 Endonuclease IV, E.coli (2 U/uL) Each pk | 재고문의 | pk | 293,000원 | - | 322,300원 | |
다른 상품 둘러보기
Thermo Scientific™
Endonuclease IV, E.coli (2 U/μL)
Thermo Scientific Endonuclease IV (Endo IV) recognizes apurinic/apyrimidinic (AP) sites of dsDNA and cleaves the phosphodiester bond 5` to the자세히 알아보기
Thermo Scientific Endonuclease IV (Endo IV) recognizes apurinic/apyrimidinic (AP) sites of dsDNA and cleaves the phosphodiester bond 5to the lesion generating a hydroxyl group at the 3-terminus (see Figure 1 in Supporting Data). The enzyme can also act as a 3-diesterase that is able to release 3-phosphoglycolate or 3-phosphate from the damaged ends of dsDNA. Endo IV possesses also a 3→5exonuclease activity. Its progression on substrates is sensitive to ionic strength, metal ions, EDTA, and reducing conditions. Substrates with 3-recessed ends are preferred substrates for the 3→5 exonuclease activity.
The enzyme has no requirement for Mg2+ and is fully active in the presence of EDTA in moderate concentrations.
Applications
• Studies of DNA damage and repair
• Single cell electrophoresis (comet assay)
• Antitumor drug research
• DNA structure research
• SNP analysis
사양
농도2 U/μL
효소Endonuclease
수량100 units
제품 유형Endonuclease IV
Unit SizeEach
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