Thermo Fisher Scientific NMDAR2D Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMDAR2D. Validated for WB and IHC applications. Lyophilized form with whole serum buffer, unconjugated. Suitable for research on glutamate receptor function and neurodevelopmental processes.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous (PubMed) | – | View 3 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 910–960 of human NMDAR2D conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: NMDAR2D.
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play key roles in neural plasticity, development, and neurodegeneration.
Ionotropic glutamate receptors are categorized into NMDA and kainate/AMPA receptors, both containing glutamate-gated, cation-specific ion channels.
Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven subunits (GluR-1 to -7).
The NMDA receptors exhibit slow kinetics and high Ca²⁺ permeability, composed of five subunits: epsilon 1–4 and one zeta subunit.
The zeta subunit is expressed throughout the brainstem, while epsilon subunits show limited distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: OSN00039W-100UL_NMDAR2D_O15399-1_Rabbit.svg, OSN00039W-100UL_NMDAR2D_O15399-1_Rabbit_PDP.jpeg)
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