Thermo Fisher Scientific Endothelin A Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting Endothelin A Receptor. Validated for WB and IHC (Frozen). Lyophilized form, reconstitute with deionized water. Suitable for research on vasoconstriction and G-protein signaling pathways.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)NHNTERSSHKDSMN, corresponding to amino acid residues 413–426 of rat ET-A |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Storage Conditions | -20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735760 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
This gene encodes the receptor for endothelin-1, a peptide involved in potent and long-lasting vasoconstriction.
The receptor interacts with guanine-nucleotide-binding (G) proteins, activating a phosphatidylinositol-calcium second messenger system.
Polymorphisms in this gene have been linked to migraine headache resistance.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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