Thermo Fisher Scientific Human FGFR2, His Tag Recombinant Protein

Thermo Fisher Scientific Human FGFR2, His Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: N/A

Product Specifications

Product Specific Information

• Spin prior to use for maximum recovery.
• For 5 µg, 10 µg, and 20 µg sizes, use material directly from original packaging.
• For larger sizes, aliquoting may reduce freeze/thaw cycles (do not prepare aliquots below 20 µL).
• Never store kinase diluted.
• Properly stored at -80°C, guaranteed for 6 months from date of purchase.

Protein Form: Recombinant, Catalytic Domain, Cytoplasmic

Target Information

FGFR2 (Fibroblast Growth Factor Receptor 2) is a receptor tyrosine kinase involved in key cellular functions such as:

• Angiogenesis
• Mitogenesis
• Osteogenesis
• Myogenesis
• Carcinogenesis
• Cellular differentiation
• Tissue repair after injury

FGFR family members differ in ligand affinities and tissue distribution.
Mutations in FGFR2 are associated with various syndromes including:

• Crouzon syndrome
• Pfeiffer syndrome
• Craniosynostosis
• Apert syndrome
• Jackson-Weiss syndrome
• Beare-Stevenson cutis gyrata syndrome
• Saethre-Chotzen syndrome
• Syndromic craniosynostosis

Multiple alternatively spliced transcript variants encoding different isoforms have been noted.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.