Thermo Fisher Scientific ALDH3A1 Polyclonal Antibody
인체 ALDH3A1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. KLH 결합 합성 펩타이드로 면역생성되었으며, 2 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | - |
| Immunocytochemistry (ICC/IF) | - | 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 254–284 of human ALDH3A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2289338 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)+-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes.
Aldh3A1 is highly expressed in the stomach and even more strongly in the cornea, representing between 5–50% of the water-soluble protein fraction in mammalian corneas.
It is thought to protect the cornea from UV-induced oxidative stress by detoxifying reactive aldehydes and directly absorbing UV energy.
Corneas from Aldh3A1-deficient mice appear similar to wild-type; however, mice lacking both Aldh3A1 and Aldh1A1 show increased cataract formation after UVB exposure, suggesting Aldh1A1 compensates for the loss of Aldh3A1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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