Thermo Fisher Scientific GREM1 Polyclonal Antibody
Human GREM1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 ELISA에 적합. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. 안정적인 PBS/glycerol buffer 구성으로 장기 보관 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 44–143 of human GREM1 (NP_001178252.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.17 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804704 |
Product Specific Information
- Immunogen sequence:
ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD - Positive Samples: SH-SY5Y, HT-29, A-431, LO2
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13–q15.
DRM-specific mRNA is expressed in various human tissues including brain, ovary, intestine, and colon.
Down-regulation of DRM may be associated with tumor progression, supporting its role in neuroembryological development and carcinogenesis.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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