Thermo Fisher Scientific CD8 Monoclonal Antibody (3B5), Qdot 800
CD8 항원을 인식하는 Mouse IgG2a 단클론 항체로, Qdot 800 형광체가 결합된 제품입니다. 인간 시료에 반응하며 Flow Cytometry에 적합합니다. 고순도 정제된 액상 형태로 안정적인 형광 신호를 제공합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CD8 Monoclonal Antibody (3B5), Qdot 800
Applications
- Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
- View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B5 |
| Immunogen | Recognizes the CD8 antigen |
| Conjugate | Qdot™ 800 |
| Excitation / Emission Max | 300 / 792 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | 0.05M borate, pH 8.3, with 1M betaine |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2556513 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 405
- Alexa Fluor 647
- Alexa Fluor 700
- APC
- APC-Alexa Fluor 750
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Cyanine5.5
- PE-Cyanine7
- PE-Texas Red
- PerCP
- Qdot 605
- Qdot 655
- Qdot 705
- TRI-COLOR
- Request custom conjugation
Target Information
Cluster of differentiation 8 (CD8) is a type I transmembrane glycoprotein of the immunoglobulin receptor family that plays a crucial role in signal transduction, T cell differentiation, and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8α and CD8β, functioning as a co-receptor with TCR for MHC-I molecules. It is also found on subsets of T cells, NK cells, monocytes, and dendritic cells as homodimers of CD8α. Engagement of MHC-I/peptide complexes triggers Lck recruitment, leading to lymphokine production and cytotoxic T lymphocyte (CTL) activation. Activated CTLs are key to pathogen and tumor cell clearance. Differentiation of naive CD8+ T cells into CTLs is enhanced by IL-2, IL-12, and TGF-β1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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