Thermo Fisher Scientific SARS-CoV-2 RBD Neutralizing Monoclonal Antibody (OTI1C2), TrueMAB
SARS-CoV-2 RBD 중화용 단클론 항체로 ELISA 및 중화시험에 적합. 마우스 IgG1 형식의 TrueMAB 제품으로 Spike RBD에 특이적 결합. 단백질 A/G 정제, 동결건조 형태로 안정적 보관 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:5,000–1:10,000
Neutralization (Neu)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Recombinant fusion protein of SARS-CoV-2 Spike RBD protein and virion surface domain of membrane protein (M-protein) produced in HEK293 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | See Label |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The CoV Spike (S) protein plays a crucial role in viral attachment, fusion, and entry, making it a key target for antibody development, entry inhibitors, and vaccines.
The Spike protein receptor-binding domain (RBD, S-RBD) binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors, with SARS-CoV-2 RBD showing higher affinity than SARS-CoV RBD.
S1 contains an RBD that specifically binds to ACE2 receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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