Thermo Fisher Scientific IGF2BP3 Polyclonal Antibody
Thermo Fisher Scientific의 IGF2BP3 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 항체입니다. Western blot, IHC, Flow cytometry에 적합하며 Protein A로 정제된 액상 형태입니다. IMP-3 단백질을 표적으로 하며 암 관련 연구에 활용됩니다.
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- PA586040
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:400 | - |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human IMP-3 (aa 352–579) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802841 |
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family. It is expressed during embryogenesis and in certain malignancies. IMP-3 is found in malignant melanoma but not in benign nevi, even when dysplastic features are present. It is expressed at higher levels in melanomas than in Spitz nevi and more in metastatic melanomas than in thin melanomas. IMP-3 may play a role in the progression of malignant melanoma and in regulating tumor biological behavior.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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