Thermo Fisher Scientific GNB1 Polyclonal Antibody
Zebrafish GNB1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. KLH 결합 합성 펩타이드(1–30 aa)로부터 유래하였으며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. PBS(pH 7.4) 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications
Tested Application
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–30 amino acids from the N-terminal region of DANRE gnb1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718496 |
Target Information
Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process begins when rhodopsin absorbs light within the retina, activating transducin, a GTP-binding protein. Activated transducin promotes hydrolysis of cGMP by phosphodiesterase (PDE), leading to closure of ion channels and membrane hyperpolarization, resulting in signal transmission. Rhodopsin activity is terminated by phosphorylation followed by arrestin binding. The subunit composition of transducin differs between photoreceptor cells — rod transducin (Trα, Tβ, Tγ) and cone transducin (Tcα, Tβ, Tγ) — contributing to their differential light sensitivities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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