Thermo Fisher Scientific MST4/MASK Polyclonal Antibody
MST4/MASK 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot 및 Immunoprecipitation에 사용 가능. 인간 반응성, 항원 친화 크로마토그래피 정제, 액상 형태로 제공되며 연구용으로만 사용.
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Applications
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): 1–4 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 300–350 of human Mammalian Ste20-like Kinase 4 (Mst3 and SOK1-related kinase) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
MST4 is a member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The gene product belongs to the GCK group III family of kinases, which are a subset of the Ste20-like kinases.
The encoded protein contains an amino-terminal kinase domain and a carboxy-terminal regulatory domain that mediates homodimerization. It localizes to the Golgi apparatus and is activated by binding to the Golgi matrix protein GM130.
MST4 is cleaved by caspase-3 in vitro and may function in the apoptotic pathway. Several alternatively spliced transcript variants have been described, though the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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