Thermo Fisher Scientific PCGF3 Polyclonal Antibody

Thermo Fisher Scientific PCGF3 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:2,000
• Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:500

Product Specifications

Target Information

Phosphorylase kinase is a hexadecameric enzyme composed of four copies of four subunits encoded by PHKA, PHKB, PHKG, and PH genes. This serine/threonine-specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, releasing glucose-1-phosphate from glycogen.
PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit with regulatory functions controlled by phosphorylation. Defects in PHKB cause glycogen storage disease type 9B, characterized by mild hepatomegaly, slightly elevated transaminase and plasma lipids, no clinical muscle involvement, and gradual improvement with age. Four isoforms of PHKB are produced via alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.