Thermo Fisher Scientific GNAQ Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence:
  DKRGFTKLVY QNIFTAMQAM IRAMDTLKIP YKYEHNKAHA QLVREVDVEK

• Sequence homology:
  Cow: 100%
  Dog: 100%
  Guinea Pig: 100%
  Horse: 100%
  Human: 100%
  Mouse: 100%
  Rabbit: 93%
  Rat: 100%
  Zebrafish: 100%

Target Information

Guanine nucleotide-binding proteins (G proteins) are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit, resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits regulate various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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