Thermo Fisher Scientific EWSR1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL
• Publications: –

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:200–1:500
• Publications: –

Product Specifications

Product Specific Information

Immunogen sequence:
GDATVSYEDP PTAKAAVEWF DGKDFQGSKL KVSLARKKPP MNSMRGGLPP REGRGMPPPL RGGPG

Target Information

This gene encodes a multifunctional protein involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport.
The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.
Chromosomal translocations between this gene and various transcription factor genes produce chimeric proteins associated with tumorigenesis.
Mutations, particularly translocations, are linked to Ewing sarcoma and other neuroectodermal tumors.
Alternative splicing results in multiple transcript variants, and related pseudogenes exist on chromosomes 1 and 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.